Vendor:Thorne

Glycine

$31.00

Sku: SA512

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Estimated Delivery 10-14 Days

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Description

The amino acid glycine plays a key role in maintaining a healthy central nervous system (CNS). It is considered one of the most important inhibitory neurotransmitters in the CNS, particularly in the brainstem and spinal cord. Studies show glycine can help support memory retrieval during occasional sleep disruption, such as from jet lag or overwork. The benefits of glycine are not just limited to the CNS. Glycine also plays a key role in phase II liver detoxification by having a direct effect on toxin elimination or by increasing the level of glutathione. Glycine also helps modulate cytokines associated with metabolic health.*

Glycine is one of three amino acids needed to produce creatine, which in turn supplies energy to muscle and nerve cells.* The other two amino acids are arginine and methionine. High concentrations of glycine are found in the muscles, the skin, and other connective tissues. Approximately 30 percent of collagen is composed of glycine.

Glycine plays an important role in supporting a healthy digestive system by helping to regulate the synthesis of bile acid, which the body uses to digest fats. Glycine also plays a role in regulating the utilization of glucose during energy production.*

This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.

Suggested Use:

Take 2 capsules one to three times daily or as recommended by your health-care practitioner.

Warnings:

ALLERGY WARNING

This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

PREGNANCY

If pregnant, consult your health-care practitioner before using this product.

INTERACTIONS

There are no known adverse interactions or contraindications at publication date.

FAQs

Frequently asked question

Is glycine worth buying as a supplement, or can I get enough from food alone?

While glycine is found in protein-rich foods like meat, fish, and legumes, it can be difficult to consume therapeutic amounts through diet alone. Supplementing with glycine offers a convenient, concentrated dose to support sleep quality, CNS function, and liver detoxification. If you have specific wellness goals around sleep or recovery, a glycine supplement is a practical and cost-effective addition to your daily routine.

What should I look for when comparing glycine supplements before buying?

Look for pure glycine with minimal fillers or additives. Check the dosage per serving, as most studies use 3 grams. Consider the form — powder blends easily into drinks, while capsules offer convenience. Third-party testing for purity is a strong quality indicator. Also review return policies and customer reviews to ensure you're buying from a trustworthy source with reliable quality standards.

What does glycine do for the brain and nervous system?

Glycine acts as an inhibitory neurotransmitter in the central nervous system, particularly in the brainstem and spinal cord. This means it helps calm overactive nerve signals, supporting relaxation and mental balance. Research also suggests glycine can help maintain memory retrieval when sleep is disrupted — for example, due to jet lag or periods of overwork — making it valuable for cognitive resilience.

Can glycine help with sleep?

Yes. Studies suggest glycine supports sleep quality, particularly when sleep is occasionally disrupted by factors like jet lag, shift work, or stress. It may help you fall asleep faster and feel more refreshed upon waking. Glycine is believed to lower core body temperature slightly, which signals the body to prepare for sleep. It is not a sedative but works gently to support your natural sleep cycle.

What role does glycine play in liver detoxification?

Glycine is a key participant in phase II liver detoxification, the stage where the liver neutralizes and prepares toxins for elimination from the body. It works by conjugating — or binding to — harmful compounds, making them water-soluble and easier to excrete. Supporting this process may help reduce the burden on your liver, especially for those exposed to environmental toxins or who follow demanding lifestyles.

Who can benefit most from taking a glycine supplement?

Glycine may benefit people experiencing occasional sleep disruption, those looking to support liver health, athletes focused on recovery, and anyone wanting to support a healthy nervous system. It's also popular among individuals with high-stress lifestyles or irregular schedules like frequent travelers. Since glycine is naturally produced in the body but sometimes in insufficient amounts, supplementation can help fill nutritional gaps for a broad range of people.

Glycine

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Frequently asked question