Description

Riboflavin, also known as vitamin B2, is necessary for the body to be able to activate vitamin B6.* Riboflavin is also necessary for the body's conversion of tryptophan to niacin, and the conversion of folate to folate's various active forms.* In addition, riboflavin plays a crucial role in the metabolism of fats and glucose, the synthesis of red blood cells, healthy methylation, and the production and regulation of certain hormones.*

To be utilized by the body, however, riboflavin must first be converted to its active form – riboflavin 5'-phospate (R5P). A compromised digestive system, however, can adversely affect the body's ability to convert riboflavin to R5P.* And certain prescription medications can also compromise the absorption of riboflavin, putting it in a state of deficiency. Thorne's Riboflavin 5'-Phosphate, which is not derived from yeast, provides supplementation with a bioactive, tissue ready form of riboflavin that can be optimally utilized in the body.*

This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.

Suggested Use:

Take 1 capsule one to three times daily or as recommended by your health-care practitioner.

Warnings:

ALLERGY WARNING

This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

PREGNANCY

If pregnant, consult your health-care practitioner before using this product.

INTERACTIONS

There are no known adverse interactions or contraindications at publication date.

FAQs
Frequently asked question

Is Riboflavin 5'-Phosphate worth buying over regular riboflavin supplements?

Yes, Riboflavin 5'-Phosphate is the active, coenzyme form of vitamin B2, meaning your body can use it immediately without needing to convert it first. Regular riboflavin requires conversion in the body, which some people do less efficiently. If you want faster, more reliable absorption and utilization, the 5'-Phosphate form is generally considered the superior choice for supporting methylation and overall B2 function.

What is your return policy if Riboflavin 5'-Phosphate doesn't work for me?

We stand behind our products with a satisfaction guarantee. If you're not happy with your purchase, contact our customer support team within the return window noted on our website for a full refund or exchange. We recommend reviewing our returns page for specific timelines and conditions. Your confidence in our supplements matters, and we want to make the process as simple as possible.

What is Riboflavin 5'-Phosphate and how is it different from regular vitamin B2?

Riboflavin 5'-Phosphate is the active coenzyme form of vitamin B2. Unlike standard riboflavin, it doesn't require conversion by the body to become usable. This makes it especially beneficial for people with certain metabolic differences who may struggle to convert riboflavin efficiently. It supports key functions including methylation, fat and glucose metabolism, and the activation of vitamins B6 and folate.

Why is riboflavin important for methylation?

Riboflavin plays a critical supporting role in the methylation cycle by helping activate folate into its various active forms and supporting the conversion of tryptophan to niacin. Healthy methylation is essential for DNA repair, mood regulation, detoxification, and cardiovascular health. Without adequate riboflavin, the methylation process can become less efficient, potentially affecting many downstream bodily functions.

Who may benefit most from taking Riboflavin 5'-Phosphate?

People who have difficulty converting standard riboflavin, those supporting their methylation pathways, individuals with certain genetic variants like MTHFR, or anyone looking to optimize B-vitamin metabolism may benefit most. It's also helpful for those wanting to support energy production, healthy red blood cell formation, and hormonal balance. Always consult your healthcare provider before starting any new supplement.

How should I take Riboflavin 5'-Phosphate for best results?

Follow the dosage instructions on the product label or as directed by your healthcare provider. Riboflavin is water-soluble, so taking it with a meal can support absorption and minimize any stomach sensitivity. Because it works closely with other B vitamins, some people take it alongside a broader methylation support protocol. Consistent daily use is typically recommended to maintain adequate levels.

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