Vendor:Thorne

PharmaGABA-250

$59.00

Sku: SP662

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Estimated Delivery 10-14 Days

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Description

Gamma-aminobutyric acid (GABA) is a major calming brain chemical or neurotransmitter.* Clinical studies show that the natural form of GABA that is in Thorne's PharmaGABA can decrease the brain's stress-related beta waves and increase the production of its alpha-waves, creating a profound sense of physical relaxation while maintaining mental focus.* Other studies have shown reduced pupil diameter, heart rate, and two natural biomarkers of stress – salivary cortisol and chromogranin A – all signs of relaxation.* In addition, studies also indicate GABA can enhance sleep.* In a head-to-head, double-blind trial of natural PharmaGABA versus synthetic GABA, the synthetic GABA did not demonstrate these positive effects.* PharmaGABA-250 offers 250 mg of natural GABA per capsule, while PharmaGABA-100 offers 100 mg per capsule. Both are non-habit forming.

In a recent study of the effect of nutrient supplementation on muscle mass, 21 males, average age 39, who did not exercise regularly, were given 10 grams of whey protein or 10 grams of whey protein plus 100 mg of PharmaGABA daily for 12 weeks. Both groups participated in twice weekly 60-minute strength training sessions that consisted of leg presses, leg extensions, leg curls, chest presses, and pull-downs. Total body lean muscle mass increased significantly in the whey protein-plus-PharmaGABA group compared to the whey-only group.*

The natural GABA in Thorne's PharmaGABA suite is produced via a fermentation process that utilizes Lactobacillus hilgardii, the same bacteria that is used to ferment cabbage in the preparation of the traditional Korean dish known as kimchi.

This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.

Suggested Use:

Take 1 capsule one to three times daily or as recommended by your health-care practitioner.

Warnings:

ALLERGY WARNING

This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.=

PREGNANCY WARNING

If pregnant, nursing, or trying to conceive do not use this product.

INTERACTIONS

There are no known adverse interactions or contraindications at publication date.

FAQs

Frequently asked question

Is PharmaGABA-250 worth buying for stress and relaxation?

Yes, PharmaGABA-250 is a well-researched option for those seeking natural stress relief. It uses a clinically studied natural form of GABA shown to reduce stress biomarkers like cortisol and chromogranin A, while promoting calm focus. Unlike synthetic alternatives, this natural form has demonstrated measurable effects on brain wave activity. If you struggle with stress, tension, or mental restlessness, it's a solid investment backed by real science.

Where can I buy PharmaGABA-250 and is it available in different sizes?

PharmaGABA-250 is available directly on this product page, ensuring you receive an authentic product. Currently, it is offered in the 250 mg per serving formulation. Purchasing directly from an authorized source guarantees product quality, proper storage handling, and access to customer support if you have questions about your order or need assistance with returns.

What is GABA and how does it support relaxation?

GABA (gamma-aminobutyric acid) is the brain's primary calming neurotransmitter. It works by reducing neuronal excitability, helping your nervous system shift from an overstimulated state to a calmer one. PharmaGABA-250 uses a naturally derived form clinically shown to increase alpha brain waves, associated with relaxed alertness, while decreasing beta waves linked to stress and anxiety — all without causing drowsiness.

What makes the natural form of GABA different from synthetic GABA?

The natural form of GABA in PharmaGABA is produced through a fermentation process, which may allow it to cross the blood-brain barrier more effectively than synthetic versions. Clinical studies specifically using this natural form have demonstrated measurable reductions in stress markers like cortisol, heart rate, and pupil diameter — benefits that have not been consistently shown with synthetic GABA supplements.

Can PharmaGABA-250 help with focus while also reducing stress?

Yes, that's one of its key benefits. Research shows PharmaGABA promotes alpha brain wave activity, which is associated with a calm yet mentally focused state — similar to what you might experience during meditation. Unlike sedatives or harsh calming agents, it supports physical relaxation without impairing mental clarity, making it suitable for daytime use when you need to stay productive under pressure.

Are there any clinical studies supporting PharmaGABA-250's effectiveness?

Yes, multiple clinical studies support the natural GABA form used in PharmaGABA-250. Research has demonstrated decreased stress-related beta brain waves, increased calming alpha waves, reduced salivary cortisol, lower chromogranin A levels, and decreased heart rate and pupil diameter — all recognized biomarkers of physical and psychological stress. These findings make PharmaGABA one of the more scientifically substantiated natural relaxation supplements available.

PharmaGABA-250

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