Methyl-Guard Plus

Various conditions and stressors can have an adverse impact on the body’s methylation cycle. Nutrient deficiencies, environmental exposures, and other aspects of a modern lifestyle can cause inefficient methylation. In addition, approximately 60 percent of U.S. adults have a genetic variation that makes it difficult for their methylation cycle to function optimally.

Thorne’s Methyl-Guard Plus features betaine (trimethylglycine), methylated vitamin B12 (methylcobalamin) and folate (5-MTHF), as well as the active forms of vitamins B2 and B6, for providing efficient nutritional support for the body’s methylation challenges.*

Benefits of Thorne Methyl-Guard Plus

• Nutritional support for individuals who have MTHFR gene variations*
• Enhanced cellular energy production fights occasional fatigue*
• Helps maintain a healthy homocysteine level in the blood, which supports cardiovascular, cognitive, and bone health*
• Promotes fat metabolism and lean body composition*
• Supports neurotransmitter production – natural chemicals that play an important role in nervous system functions, like attention, focus, mood, and sleep*
• Promotes liver detoxification of many substances, including hormones like estrogen*

Why is methylation important?

Methylation is a simple reaction where a small molecule known as a “methyl group” is transferred from one substance to another. Methylation significantly impacts many biochemical reactions in the body and plays a beneficial role in:

• Cardiovascular health
• Cellular energy production
• Fat metabolism
• Neurological function
• DNA production
• Liver detoxification processes
• Eye health
• Histamine balance

Who can benefit from Thorne Methyl-Guard Plus

• Individuals with variations to MTHFR and other genes that adversely affect methylation*
• Aging individuals wanting to support their cardiovascular, cognitive, and metabolic health*
• Women seeking support for estrogen metabolism and bone health*
• Individuals wanting nutritional support for fat metabolism and maintenance of a healthy body composition*
• Anyone with limited consumption of methylation-supportive foods like green leafy vegetables, legumes, and cruciferous vegetables

Features of Thorne Methyl-Guard Plus

• Betaine, also known as trimethylglycine, is a superior methyl donor 
• The methylated forms of vitamin B12 (methylcobalamin) and folate (5-MTHF) benefit individuals with certain gene mutations*
• Active forms of vitamins B2 and B6 – key cofactors in methylation processes
• B vitamins in their active, tissue-ready forms means your body gets the greatest benefit with the least additional work*
• Robust methylation support in fewer capsules per day than Thorne’s original Methyl-Guard

This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.

Suggested Use:

Take 1-3 capsules daily or as recommended by your health-care practitioner.

Warnings:

ALLERGY WARNING

This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

PREGNANCY

If pregnant, consult your health-care practitioner before using this product.

INTERACTIONS

5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, 5-MTHF has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.