Description

Thorne offers melatonin in both 3 mg (Melatonin-3) and 5 mg (Melatonin-5) capsules. Melatonin, the primary hormone of the pineal gland, is a powerful "chronobiotic" that helps maintain the body's normal circadian rhythms.* In individuals who have difficulty sleeping or who have altered circadian rhythms because of jet lag or night shift work, melatonin supplementation promotes the resynchronization of this cycle.* Supplementation can also benefit those whose difficulty sleeping is caused by the aging-related decrease in the body's ability to synthesize melatonin from the amino acid tryptophan.* Research indicates melatonin exerts its sleep-promoting efficacy by decreasing the amount of time needed to fall asleep, by promoting the ability to stay asleep, and by enhancing the depth of sleep.*

Melatonin administration from 0.3 mg to 5.0 mg has been shown to exert a sedative-like effect.* When supplemented prior to the onset of the body's normal melatonin secretion, even a low amount of melatonin can promote sleep.* Melatonin apparently enhances the effect of gamma-aminobutyric acid (GABA) via direct interaction with GABA receptors, thus resulting in relaxation.* Thorne's Melaton-3 supplies three mg of melatonin in each capsule, and Melaton-5 supplies 5 mg per capsule and is used when a higher amount of melatonin is desired. Melatonin also has significant antioxidant activity.* Adequate melatonin levels have been reported to be a positive factor in cardiovascular, neuroendocrine, GI, and bone health.*

This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.

Suggested Use:

Take 1 capsule at bedtime or as recommended by your health-care practitioner.

Warnings:

ALLERGY WARNING

This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

PREGNANCY WARNING

If pregnant or nursing, do not use this product.

INTERACTIONS

Because melatonin may potentiate the effect of blood-thinning medications, Melaton-5 should be used with caution or avoided in individuals on anticoagulant therapy or prior to surgery.

FAQs
Frequently asked question

What is the difference between Melatonin-3 and Melatonin-5, and which should I choose?

Melatonin-3 contains 3 mg per capsule while Melatonin-5 contains 5 mg. If you're new to melatonin, starting with the lower dose is often recommended. Melatonin-5 may be better suited for those with more significant sleep disruptions, shift work schedules, or frequent jet lag. Consult your healthcare provider to determine the right dosage for your specific needs.

Is Melatonin-5 worth buying compared to cheaper melatonin supplements?

Thorne's Melatonin-5 is manufactured to pharmaceutical-grade standards with rigorous third-party testing, ensuring purity and accurate dosing. Many budget melatonin products vary widely in actual melatonin content. If quality, consistency, and a trusted brand matter to you, Melatonin-5 is a worthwhile investment for reliable sleep support.

What does melatonin actually do in the body?

Melatonin is a hormone naturally produced by the pineal gland that signals your body it's time to sleep. It acts as a chronobiotic, helping regulate your internal circadian clock. Levels naturally rise in the evening and fall in the morning. Supplementing with melatonin can help reinforce this cycle when it becomes disrupted.

Can Melatonin-5 help with jet lag?

Yes. Melatonin is well-studied for helping travelers resynchronize their circadian rhythms after crossing time zones. Taking Melatonin-5 at the appropriate local bedtime can help your body adjust faster, reducing jet lag symptoms like daytime fatigue and nighttime wakefulness. It's a popular, non-habit-forming option for frequent flyers.

Is melatonin safe to take every night?

Melatonin is generally considered safe for short-term nightly use. It is non-habit-forming and does not cause dependency like some prescription sleep aids. However, for long-term nightly use, it's best to consult a healthcare provider. Melatonin works best when combined with good sleep hygiene practices.

Who should consider taking Melatonin-5?

Melatonin-5 is ideal for adults experiencing occasional sleeplessness, jet lag, or disrupted sleep from night shift work. It may also benefit those whose circadian rhythm has shifted due to age or lifestyle factors. It is not recommended for children, pregnant women, or nursing mothers without prior medical guidance.

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