Description

Busy schedules and non-stop activities leave you feeling depleted and distracted. It’s what many describe as brain fog. Thorne’s formula helps clear your head with key nutrients that support focus, attention, and mental function.* Brain Factors combines a unique coffee fruit extract with our exclusive Nicotinamide Riboside (NR) to support optimal levels of BDNF and NAD+ – two substances in the body that are adversely affected by aging – thereby promoting optimal brain health and cognition to help you stay mentally agile.* 


Key benefits from supporting BDNF and NAD+ with Brain Factors

  • Promotes memory and focus by enhancing the communication between brain cells*
  • Promotes attention and learning by supporting growth and development of new brain cells*
  • Supports cognitive health at every age*
  • Helps decrease brain fog in older individuals or those who experience high amounts of stress*


What is BDNF and why is it important?

BDNF – brain-derived neurotrophic factor – is a protein that helps the brain flourish, providing support for brain cells and the nervous system. As we age, the level of BDNF declines, and a low level of BDNF is associated with multiple negative effects of aging. 

Coffee fruit extract helps maintain a healthy BDNF level, which:

  • Promotes the development and growth of new brain cells*
  • Supports the communication pathways between nerve cells*
  • Supports cognitive functions like learning, memory, and focus*
  • Supports balanced neurotransmitters – natural chemicals that regulate nervous system functions like mood and sleep*


Why is NAD+ important for healthy aging?

NAD+ – nicotinamide adenine dinucleotide – is an important coenzyme found in every cell. NAD+ is crucial for supporting numerous metabolic and cellular functions in the body. However, NAD+ declines significantly with age, as well as from excessive stress, which can lead to reduced vitality. NR promotes a healthy level of NAD+, which in turn:

  • Promotes healthy aging by helping maintain energy production at the cellular level*
  • Protects against oxidative stress and the DNA damage that accompanies it*
  • Supports normal circadian rhythm – the body’s natural sleep-wake cycle*
  • Helps increase the number and health of mitochondria in cells, thus benefiting mitochondrial metabolism*
  • Supports cellular repair processes*


The added benefits of betaine

Supporting the body’s methylation processes optimize the benefits of NR.* Betaine (also known as trimethylglycine) is a superior methyl donor in the body – each molecule of betaine supplies three methyl groups. By promoting efficient methylation, the betaine in Thorne’s Brain Factors:

  • Supports important cognitive functions in aging adults, like memory and focus*
  • Enhances optimal metabolism of NAD+*
  • Helps maintain balanced levels of neurotransmitters in the brain*
  • Promotes a healthy level of homocysteine in the blood, which supports cognitive and cardiovascular health*


This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.

Suggested Use:

Take 1 capsule daily or as recommended by your health-care practitioner.

Warnings:

ALLERGY WARNING

This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

PREGNANCY

If pregnant, consult your health-care practitioner before using this product.

INTERACTIONS

There are no known adverse interactions or contraindications at publication date.

FAQs
Frequently asked question

Is Brain Factors worth buying for everyday brain fog and focus issues?

Yes, Brain Factors is a strong choice if you struggle with brain fog, low focus, or mental fatigue from a busy lifestyle. It combines coffee fruit extract and Nicotinamide Riboside (NR) to support BDNF and NAD+ levels — two key markers of brain health that decline with age. Many users report noticeable improvements in clarity and attention. It's especially valuable if you want a science-backed supplement from a trusted brand like Thorne.

Where can I buy Brain Factors and does it come with a return policy?

Brain Factors is available directly through Thorne's official website and authorized retailers. Purchasing from an official source ensures product authenticity and access to customer support. Thorne typically offers a satisfaction guarantee, so if you're not happy with your purchase, you can contact their support team to explore return or refund options. Always check the current return policy on the product page before ordering.

What is BDNF and why does it matter for brain health?

BDNF, or Brain-Derived Neurotrophic Factor, is a protein that supports the growth and maintenance of neurons in the brain. Higher BDNF levels are associated with better memory, learning, and mental clarity. Aging and chronic stress can reduce BDNF levels, contributing to cognitive decline and brain fog. Brain Factors is formulated to help support healthy BDNF levels using coffee fruit extract.

What is Nicotinamide Riboside (NR) and what does it do?

Nicotinamide Riboside is a form of vitamin B3 that the body converts into NAD+, a coenzyme essential for cellular energy production. NAD+ levels naturally decline with age, affecting mental and physical performance. By boosting NAD+, NR helps support brain cell function, energy metabolism, and cognitive health. Thorne uses an exclusive form of NR in Brain Factors to maximize absorption and effectiveness.

How long does it take to notice results from Brain Factors?

Results vary by individual, but many users begin noticing improvements in focus and mental clarity within two to four weeks of consistent use. Like most nutritional supplements, Brain Factors works best when taken regularly over time. Factors like sleep quality, diet, and stress levels can also influence how quickly you notice benefits. For best results, follow the recommended dosage on the label.

Can anyone take Brain Factors, or is it intended for a specific age group?

Brain Factors is designed for adults who want to support cognitive function, focus, and mental clarity. It's particularly beneficial for those experiencing age-related cognitive changes, since BDNF and NAD+ levels decline over time. However, anyone with a busy lifestyle and focus challenges may benefit. If you are pregnant, nursing, or taking medications, consult your healthcare provider before starting any new supplement.

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