Description

B-Complex #12 contains a balance of essential B vitamins plus choline, with extra vitamin B12. Unlike many multi-B vitamin formulas on the market, Thorne’s B-Complex #12 contains the active, tissue-ready forms of several B vitamins. 

Supplementing with the active forms of the B vitamins is important to everyone, especially individuals who might not be able to convert non-active B vitamins to their active forms in the liver because of compromised liver function, poorly functioning enzymes, digestive disorders, or increasing age.


Benefits of Thorne B-Complex #12

  • Supports healthy nerve cells and an optimally functioning nervous system*
  • Promotes normal red blood cell formation*
  • Supports tissue and cellular repair*
  • Provides vitamin B12 and folate in their methylated forms to support normal methylation and homocysteine metabolism*
  • Promotes DNA synthesis*
  • Supports cellular energy production*


Who can benefit from Thorne B-Complex #12 

  • Individuals who have an MTHFR gene variant 
  • Anyone seeking additional support for a healthy nervous system 
  • Individuals taking certain medications that can deplete B-vitamins 
  • Aging individuals who might not be able to convert B vitamins to their active forms as efficiently 
  • Those who do not consume adequate B-12 and folate in the diet 


Features of Thorne B-Complex #12

  • B vitamins in their active, tissue-ready forms*
  • The methylated forms of B12 (as methylcobalamin) and folate (as 5-MTHF) benefit individuals who have a specific gene variants
  • Ingredients are not derived from yeast 


This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.

Suggested Use:

Take 1 capsule one to three times daily or as recommended by your health-care practitioner.

Warnings:

ALLERGY WARNING

This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

PREGNANCY

If pregnant, consult your health-care practitioner before using this product.

INTERACTIONS

5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.

FAQs
Frequently asked question

Is B-Complex #12 worth buying compared to other B-vitamin supplements?

B-Complex #12 stands out because it uses active, tissue-ready forms of B vitamins that your body can use immediately, unlike many standard formulas requiring liver conversion. This makes it especially valuable for people with digestive issues, liver concerns, or enzyme inefficiencies. If you want a B-complex that works efficiently without conversion steps, B-Complex #12 offers a meaningful advantage over typical options on the market.

Where can I buy B-Complex #12 and is it available for subscription or bulk purchase?

B-Complex #12 is available directly through our online store. We offer convenient subscription options that save you money and ensure you never run out. Bulk purchasing may also be available depending on current promotions. Buying directly ensures you receive a genuine, properly stored product backed by our customer support team.

What does B-Complex #12 do for your body?

B-Complex #12 supports energy production, nervous system health, red blood cell formation, and metabolism. The included B vitamins—such as B6, B12, folate, and others—play essential roles in converting food into energy and maintaining cognitive function. The added choline supports brain and liver health, making this a well-rounded formula for overall daily wellness.

Why does B-Complex #12 contain extra vitamin B12?

Vitamin B12 is critical for nerve function, DNA synthesis, and red blood cell production, yet many people are deficient—especially older adults, vegetarians, and vegans. B-Complex #12 includes extra B12 in its active form to ensure optimal absorption and utilization, helping address common shortfalls that a standard-dose formula might not adequately cover.

What are 'active forms' of B vitamins and why do they matter?

Active forms are B vitamins already converted into the state your body can use directly. Standard supplements often contain inactive forms that require your liver and enzymes to convert them first. If your body struggles with this conversion due to genetics, liver issues, or digestive problems, active forms bypass that step entirely, delivering nutrients more effectively and reliably.

Who should consider taking B-Complex #12?

B-Complex #12 is ideal for adults seeking daily B-vitamin support, particularly those with compromised liver function, digestive concerns, or genetic variations affecting nutrient metabolism. It's also beneficial for vegetarians, vegans, older adults, and anyone experiencing low energy or poor focus. As always, consult your healthcare provider before starting any new supplement, especially if you have existing health conditions.

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