Vendor: Thorne

5-MTHF 5 mg

$68.00

Sku: B132

Product variants

Estimated Delivery 6-10 Days

Share:

Share

Pairs well with

Description

Folate is a key component in the body’s methylation cycle, a series of biochemical reactions that play a beneficial role in multiple body systems. Heart and brain health, cellular energy production, fat metabolism, liver detoxification, and bone health all rely on a healthy methylation cycle.

Approximately 60 percent of U.S. adults have a genetic variation that makes it difficult for their methylation cycle to function optimally. For these individuals, methylated vitamins, like Thorne’s 5-MTHF, provide essential nutritional support.*

Benefits of Thorne 5-MTHF

Nutritional support for individuals who have an MTHFR gene mutation*
Supports production of key neurotransmitters – serotonin, melatonin, dopamine, and epinephrine – natural brain chemicals that play an important role in regulating brain function and mood*
Promotes cardiovascular, brain, and bone health by maintaining a healthy methylation cycle and a normal homocysteine level*
Supports healthy fetal brain and spinal cord development*
Promotes blood and nerve cell health*

Features of Thorne 5-MTHF

Suitable for individuals who have an MTHFR gene mutation*
Active, methylated folate (5-MTHF) means your body gets the highest benefit with the least additional work
1 mg 5-MTHF is recommended for support of fetal development during pregnancy*
Easy-to-take, small capsules

This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.

Suggested Use:

Take 1 capsule one to two times daily or as recommended by your health-care practitioner.

Warnings:

ALLERGY WARNING

This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.

PREGNANCY

If pregnant, consult your health-care practitioner before using this product.

INTERACTIONS

5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.

FAQs

Frequently asked question

Is Thorne 5-MTHF 5 mg worth buying if I already take a regular folic acid supplement?

Yes, especially if you have the MTHFR genetic variation. Regular folic acid must be converted by your body before it can be used, and about 60% of people have difficulty making that conversion efficiently. 5-MTHF is already in its active, methylated form, meaning your body can use it immediately without conversion. If you suspect methylation issues or have confirmed MTHFR variants, 5-MTHF is a meaningfully better choice.

Where can I buy Thorne 5-MTHF 5 mg and is it available for subscription or auto-ship?

Thorne 5-MTHF 5 mg is available directly on this page. Purchasing here ensures you receive an authentic product. Many customers opt for a subscription or auto-ship option when available, which can offer cost savings and convenience. Check the product page for current pricing, bundle deals, and subscription availability to get the best value.

What is 5-MTHF and how is it different from regular folate?

5-MTHF (5-methyltetrahydrofolate) is the active, bioavailable form of folate. Unlike synthetic folic acid, it doesn't require enzymatic conversion in the body. This makes it especially beneficial for people with MTHFR gene variants, which impair the body's ability to convert standard folate into its usable form. Taking 5-MTHF ensures your body receives folate it can use right away.

What are the main health benefits of taking 5-MTHF?

5-MTHF supports the body's methylation cycle, which influences heart health, brain function, cellular energy production, fat metabolism, liver detoxification, and bone health. Adequate folate levels are also critical during pregnancy for healthy fetal development. By using an active form of folate, 5-MTHF helps ensure these vital processes run efficiently, particularly for those with genetic variations affecting folate metabolism.

Who should consider taking 5-MTHF 5 mg?

This supplement is ideal for individuals with MTHFR gene variants, those with low folate levels, people planning pregnancy, or anyone looking to support cardiovascular and cognitive health. Since roughly 60% of U.S. adults carry a genetic variation affecting folate conversion, many people may benefit. Consult your healthcare provider before starting any new supplement, especially if you are pregnant or managing a health condition.

Are there any side effects or interactions I should know about with 5-MTHF?

5-MTHF is generally well tolerated. However, in some sensitive individuals, higher doses may cause mild symptoms like irritability or sleep disturbances as methylation pathways become more active. It may interact with certain medications, including methotrexate or anticonvulsants. Always consult your doctor or pharmacist before adding 5-MTHF to your routine, particularly if you take prescription medications or have an existing health condition.

5-MTHF 5 mg

Request Price

Suggested Use:

Warnings:

Frequently asked question