{"title":"Energy - Supplements","description":"\u003ch2\u003eRevitalize Your Day with Energy Supplements\u003c\/h2\u003e\u003cp\u003e\u003cstrong\u003eUnlock boundless energy\u003c\/strong\u003e and seize every moment with our dynamic range of Energy - Supplements. Designed to fuel your ambition, these potent formulas power your body to perform at its peak. Feel the invigoration from nature’s own sources, handpicked to enhance your vitality and provide sustained energy.\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBoost Endurance:\u003c\/strong\u003e Never miss a beat. Whether chasing deadlines or hitting the gym, our supplements provide the stamina you need to push through.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnhance Mental Clarity:\u003c\/strong\u003e Wave goodbye to midday slumps. Fine-tuned ingredients sharpen focus, allowing you to think clearly and react swiftly.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePromote Alertness:\u003c\/strong\u003e Stay on top of your game all day. Our energy support keeps fatigue at bay, ensuring you’re at your most alert, from sunrise to sunset.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNatural Ingredients:\u003c\/strong\u003e Harness the clean power of nature. Our supplements include carefully selected herbs and vitamins, ensuring you energize the smart way.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEffortless Integration:\u003c\/strong\u003e Seamlessly incorporate our energy boosters into your routine. Convenient formats make it easy to enhance your lifestyle.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eExperience an electric surge of \u003cem\u003ewell-being\u003c\/em\u003e as these energy-boosters drive you towards your goals. Break past plateaus and discover what it means to live at full throttle. Feel a profound, natural lift that not only powers your day but supports long-term health. From students tackling intense study schedules to professionals navigating demanding workloads, these supplements are tailored to diverse energy needs, making them a must-have for anyone seeking to amplify their potential.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eTransform your lifestyle\u003c\/strong\u003e into one bustling with energy, focus, and clarity. Let the hustle and bustle refine your success as each supplement in our category unfurls the might and power of boosted vitality. \u003c\/p\u003e\u003cp\u003eVisit now and \u003cem\u003eembrace the energizing trail\u003c\/em\u003e ahead with unwavering confidence. \u003ca href=\"#\"\u003eExplore our Energy Supplements\u003c\/a\u003e today and ignite the powerhouse within you! Let’s get energized!\u003c\/p\u003e","products":[{"product_id":"vitamin-b12","title":"Vitamin B12","description":"\u003cp\u003eVitamin B12 is essential for numerous processes in the body. While B12 is often found in different forms in nutritional supplements, clinical evidence indicates that the body uses the methylcobalamin form of B12 more efficiently than other forms, such as cyanocobalamin. Thorne's Vitamin B12 as methylcobalamin provides vitamin B12 in its active, tissue-ready form.\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBenefits of Thorne Vitamin B12 \u003c\/strong\u003e\u003c\/p\u003e\u003cul style=\"list-style-type: disc;\"\u003e\n\u003cli\u003eSupports healthy nerve function and feeling*\u003c\/li\u003e\n\u003cli\u003ePromotes the body’s methylation pathways*\u003c\/li\u003e\n\u003cli\u003eBalances circadian rhythms to enhance restful sleep*\u003c\/li\u003e\n\u003cli\u003eSupports healthy homocysteine levels*\u003c\/li\u003e\n\u003cli\u003ePromotes cardiovascular health*\u003c\/li\u003e\n\u003cli\u003eBenefits cognitive function*\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWho can benefit from Thorne Vitamin B12 \u003c\/strong\u003e\u003c\/p\u003e\u003cul style=\"list-style-type: disc;\"\u003e\n\u003cli\u003eVegans or vegetarians whose diets are low in B12\u003c\/li\u003e\n\u003cli\u003eA person with low stomach acid\u003c\/li\u003e\n\u003cli\u003eThe elderly who may eat fewer B12-rich foods and might not absorb it as well\u003c\/li\u003e\n\u003cli\u003eAnyone with anemia because B12 is necessary of red  blood cell formation\u003c\/li\u003e\n\u003cli\u003eIndividuals on certain medications, including metformin, proton pump inhibitors, and seizure medications\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cspan data-teams=\"true\"\u003e\u003cspan dir=\"ltr\"\u003eThis product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\u003ch3\u003eSuggested Use:\u003c\/h3\u003e\u003cp\u003eTake 1 capsule one to three times daily or as recommended by your health-care practitioner.\u003c\/p\u003e\u003ch3\u003eWarnings:\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eALLERGY WARNING\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThis product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePREGNANCY\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eIf pregnant, consult your health-care practitioner before using this product.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThere are no known adverse interactions or contraindications at publication date.\u003c\/p\u003e","brand":"Thorne","offers":[{"title":"Default Title","offer_id":51195857305878,"sku":"B125","price":24.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0906\/1423\/5414\/files\/b125__vdc2295bdfd7f57713849ab8693465dc3ee2e45a0.png?v=1778187982"},{"product_id":"stress-management-stack","title":"Stress Management Stack","description":"\u003cp\u003eToo much daily stress will eventually take a toll on our body. The constant low-level stress that most of us encounter daily – combined with environmental pollution and diets high in refined carbohydrates – can overstimulate and overtax the adrenal glands. In addition, stress can damage the immune, cardiovascular, neurological, and endocrine systems, eventually impairing a person’s long-term health.\u003c\/p\u003e\u003cp\u003eThorne’s Stress Management Stack provides comprehensive benefits by optimizing the body’s resilience to stress, supporting adrenal functions, and promoting a calm state of mind.* \u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eThorne's Stress Management Stack includes three products:\u003c\/strong\u003e  \u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.thorne.com\/products\/dp\/ginseng-plus\" rel=\"noopener noreferrer\" target=\"_blank\"\u003e\u003cu\u003eGinseng Plus\u003c\/u\u003e\u003c\/a\u003e helps prepare the body for the impacts of stress – supporting resilience, energy, and vitality so you can perform at your best.* Korean red ginseng, lion’s mane, and Greek mountain tea support cognition, focus, memory, and mood, particularly during times of high stress.*\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.thorne.com\/products\/dp\/stress-b-complex\" rel=\"noopener noreferrer\" target=\"_blank\"\u003e\u003cu\u003eStress B-Complex\u003c\/u\u003e\u003c\/a\u003e contains an optimal balance of essential B vitamins to provide daily support for healthy brain, nerve, and adrenal function.* It contains a full B complex with extra vitamin B5, which is found in high concentrations in the adrenal glands.\u003c\/p\u003e\u003cp\u003e\u003ca href=\"https:\/\/www.thorne.com\/products\/dp\/pharmagaba-250\" rel=\"noopener noreferrer\" target=\"_blank\"\u003e\u003cu\u003ePharmaGABA-250\u003c\/u\u003e\u003c\/a\u003e features a natural source GABA, an inhibitory neurotransmitter, that acts as a \"brake\" on stress. GABA supports restful sleep when taken at night and promotes a focused but calm state of mind. Clinical studies show the natural form of GABA in Thorne's PharmaGABA can decrease the brain's stress-related beta waves and increase the production of alpha-waves, creating a profound sense of physical relaxation while maintaining mental focus.*\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBenefits of the Stress Management Stack:\u003c\/strong\u003e\u003c\/p\u003e\u003cul style=\"list-style-type: disc;\"\u003e\n\u003cli\u003eEnhances the body’s resilience to stress*\u003c\/li\u003e\n\u003cli\u003ePromotes feelings of calmness during times of stress*\u003c\/li\u003e\n\u003cli\u003eSupports cognition and elevates focus after the first use*\u003c\/li\u003e\n\u003cli\u003eEnhances mental clarity and memory during periods of stress*\u003c\/li\u003e\n\u003cli\u003eProvides needed nutrients for the adrenal glands to function*\u003c\/li\u003e\n\u003cli\u003eSupports a relaxed but focused state of mind*\u003c\/li\u003e\n\u003cli\u003eMaintains a balanced cortisol level* \u003c\/li\u003e\n\u003c\/ul\u003e\u003ch3\u003eSuggested Use:\u003c\/h3\u003e\u003cp\u003e\u003c\/p\u003e\u003cp\u003e\u003cu\u003eStress B-Complex\u0026amp;nbsp\u003c\/u\u003e\u003c\/p\u003e\u003cp\u003eTake 1 capsule one to three times daily.\u003c\/p\u003e\u003cp\u003e\u003cu\u003ePharmaGABA-250\u0026amp;nbsp\u003c\/u\u003e\u003c\/p\u003e\u003cp\u003eTake 1 capsule one to three times daily. \u003c\/p\u003e\u003cp\u003e\u003cu\u003eGinseng Plus\u0026amp;nbsp\u003c\/u\u003e\u003c\/p\u003e\u003cp\u003eTake 2 capsules daily.\u003c\/p\u003e\u003ch3\u003eWarnings:\u003c\/h3\u003enull","brand":"Thorne","offers":[{"title":"Default Title","offer_id":51195857862934,"sku":"BUN007","price":120.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0906\/1423\/5414\/files\/bun007__vdad29a120c97622927750ac5c3a9b5c903336ce8.png?v=1778015032"},{"product_id":"stress-b-complex","title":"Stress B-Complex","description":"\u003cp\u003eThorne’s Stress B-Complex is an essential choice for individuals seeking nutritional support for an overstressed lifestyle. The nutrients in Stress B-Complex work synergistically throughout the body to promote cellular energy production, healthy red blood cell formation, cognitive function, and mood.* The extra vitamin B5 (pantothenic acid), an important nutrient for healthy adrenal, nervous system, and immune function,* complements the optimal balance of eight essential B vitamins plus choline.\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBenefits of Thorne’s Stress B-Complex\u003c\/strong\u003e\u003c\/p\u003e\u003cul style=\"list-style-type: disc;\"\u003e\n\u003cli\u003eA healthy cortisol response to stress is supported by 250 mg of pantothenic acid (vitamin B5) per serving*\u003c\/li\u003e\n\u003cli\u003eCarbohydrate, protein, and fat metabolism is promoted by the enhanced production of coenzyme A with the addition of vitamin B5*\u003c\/li\u003e\n\u003cli\u003eEnhanced cellular energy production helps fight stress-related fatigue*\u003c\/li\u003e\n\u003cli\u003eNormal neurotransmitter production supports a balanced mood*\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFeatures of Thorne’s Stress B-Complex\u003c\/strong\u003e\u003c\/p\u003e\u003cul style=\"list-style-type: disc;\"\u003e\n\u003cli\u003eB vitamins in their active, tissue-ready forms means your body gets the highest benefit with the least additional work*\u003c\/li\u003e\n\u003cli\u003eThe methylated forms of B12 and folate (5-MTHF) benefit individuals with certain gene mutations*\u003c\/li\u003e\n\u003cli\u003eCholine promotes healthy brain and nervous system function*\u003c\/li\u003e\n\u003cli\u003eStress B-Complex is not derived from yeast\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eStill unsure which B-Complex to choose? Take our \u003ca href=\"https:\/\/www.thorne.com\/quizzes\/which-b-complex-is-best-for-me\" rel=\"noopener noreferrer\" target=\"_blank\"\u003eB-Complex Quiz\u003c\/a\u003e.\u003c\/p\u003e\u003cp\u003e\u003cspan data-teams=\"true\"\u003e\u003cspan dir=\"ltr\"\u003eThis product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\u003ch3\u003eSuggested Use:\u003c\/h3\u003e\u003cp\u003eTake 1 capsule one to three times daily or as recommended by your health-care practitioner.\u003c\/p\u003e\u003ch3\u003eWarnings:\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eALLERGY WARNING\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThis product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePREGNANCY\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eIf pregnant, consult your health-care practitioner before using this product.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.\u003c\/p\u003e","brand":"Thorne","offers":[{"title":"Default Title","offer_id":51195857928470,"sku":"B107","price":26.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0906\/1423\/5414\/files\/b107__v5dabbd1393b8a7ff4f391f3839b63fa757822234.png?v=1778187769"},{"product_id":"methyl-guard-plus","title":"Methyl-Guard Plus","description":"\u003cp\u003eVarious conditions and stressors can have an adverse impact on the body’s methylation cycle. Nutrient deficiencies, environmental exposures, and other aspects of a modern lifestyle can cause inefficient methylation. In addition, approximately 60 percent of U.S. adults have a genetic variation that makes it difficult for their methylation cycle to function optimally.\u003c\/p\u003e\u003cp\u003eThorne’s Methyl-Guard Plus features betaine (trimethylglycine), methylated vitamin B12 (methylcobalamin) and folate (5-MTHF), as well as the active forms of vitamins B2 and B6, for providing efficient nutritional support for the body’s methylation challenges.*\u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eBenefits of Thorne Methyl-Guard Plus\u003c\/strong\u003e\u003c\/p\u003e\u003cul style=\"list-style-type: disc;\"\u003e\n\u003cli\u003eNutritional support for individuals who have MTHFR gene variations*\u003c\/li\u003e\n\u003cli\u003eEnhanced cellular energy production fights occasional fatigue*\u003c\/li\u003e\n\u003cli\u003eHelps maintain a healthy homocysteine level in the blood, which supports cardiovascular, cognitive, and bone health*\u003c\/li\u003e\n\u003cli\u003ePromotes fat metabolism and lean body composition*\u003c\/li\u003e\n\u003cli\u003eSupports neurotransmitter production – natural chemicals that play an important role in nervous system functions, like attention, focus, mood, and sleep*\u003c\/li\u003e\n\u003cli\u003ePromotes liver detoxification of many substances, including hormones like estrogen*\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWhy is methylation important?\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eMethylation is a simple reaction where a small molecule known as a “methyl group” is transferred from one substance to another. Methylation significantly impacts many biochemical reactions in the body and plays a beneficial role in:\u003c\/p\u003e\u003cul style=\"list-style-type: disc;\"\u003e\n\u003cli\u003eCardiovascular health\u003c\/li\u003e\n\u003cli\u003eCellular energy production\u003c\/li\u003e\n\u003cli\u003eFat metabolism\u003c\/li\u003e\n\u003cli\u003eNeurological function\u003c\/li\u003e\n\u003cli\u003eDNA production\u003c\/li\u003e\n\u003cli\u003eLiver detoxification processes\u003c\/li\u003e\n\u003cli\u003eEye health\u003c\/li\u003e\n\u003cli\u003eHistamine balance\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003e \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eWho can benefit from Thorne Methyl-Guard Plus\u003c\/strong\u003e\u003c\/p\u003e\u003cul style=\"list-style-type: disc;\"\u003e\n\u003cli\u003eIndividuals with variations to MTHFR and other genes that adversely affect methylation*\u003c\/li\u003e\n\u003cli\u003eAging individuals wanting to support their cardiovascular, cognitive, and metabolic health*\u003c\/li\u003e\n\u003cli\u003eWomen seeking support for estrogen metabolism and bone health*\u003c\/li\u003e\n\u003cli\u003eIndividuals wanting nutritional support for fat metabolism and maintenance of a healthy body composition*\u003c\/li\u003e\n\u003cli\u003eAnyone with limited consumption of methylation-supportive foods like green leafy vegetables, legumes, and cruciferous vegetables\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cstrong\u003e \u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eFeatures of Thorne Methyl-Guard Plus\u003c\/strong\u003e\u003c\/p\u003e\u003cul style=\"list-style-type: disc;\"\u003e\n\u003cli\u003eBetaine, also known as trimethylglycine, is a superior methyl donor \u003c\/li\u003e\n\u003cli\u003eThe methylated forms of vitamin B12 (methylcobalamin) and folate (5-MTHF) benefit individuals with certain gene mutations*\u003c\/li\u003e\n\u003cli\u003eActive forms of vitamins B2 and B6 – key cofactors in methylation processes\u003c\/li\u003e\n\u003cli\u003eB vitamins in their active, tissue-ready forms means your body gets the greatest benefit with the least additional work*\u003c\/li\u003e\n\u003cli\u003eRobust methylation support in fewer capsules per day than Thorne’s original Methyl-Guard\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cspan data-teams=\"true\"\u003e\u003cspan dir=\"ltr\"\u003eThis product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants, such as heavy metals, pesticides, and microorganisms.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\u003ch3\u003eSuggested Use:\u003c\/h3\u003e\u003cp\u003eTake 1-3 capsules daily or as recommended by your health-care practitioner.\u003c\/p\u003e\u003ch3\u003eWarnings:\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eALLERGY WARNING\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThis product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePREGNANCY\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eIf pregnant, consult your health-care practitioner before using this product.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrently with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, 5-MTHF has not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate.\u003c\/p\u003e","brand":"Thorne","offers":[{"title":"Default Title","offer_id":51195859304726,"sku":"SF789","price":62.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0906\/1423\/5414\/files\/sf789__v91750aed7bf879ac1f9bfefec208c92da0123ca8.png?v=1778244535"},{"product_id":"methyl-guard","title":"Methyl-Guard","description":"\u003cp\u003eThe body's methylation process is key to maintaining a healthy level of homocysteine, as well as to multiple other biochemical processes involving neurotransmitters, detoxification, cardiovascular health, eye health, muscle health, bone health, and redox balance.* Maintaining a normal homocysteine level in the blood has joined having normal cholesterol and triglyceride levels as primary objectives for maintaining good cardiovascular health.* Because Methyl-Guard promotes healthy methylation, it helps maintain heart, blood vessel, cognitive, nerve, bone, and female reproductive health.* Methyl-Guard was the first nutritional supplement on the market to support homocysteine metabolism and healthy methylation using nutrients in their active, tissue-ready forms.*\u003c\/p\u003e\u003cp\u003eVarious conditions and stressors can have an adverse impact on the body’s methylation cycle. For example, nutrient deficiencies and environmental and physical stressors can cause inefficient methylation. In addition, a common human genetic mutation that restricts the activity of a key enzyme in the body involved in methylation affects approximately 60 percent of U.S. adults.  This genetic anomaly poses a significant challenge to efficient methylation – and creates an important need for nutritional support to help rectify it.\u003c\/p\u003e\u003cp\u003eMethylation – the addition of a methyl group (CH3 – one carbon attached to three hydrogens) to another molecule – is an essential and vital biochemical process in the body involved in multiple biochemical pathways involving neurotransmitters, detoxification, cardiovascular health, eye health, muscle health, bone health, and redox balance. A number of specific nutrients are necessary for the process of methylation to occur effectively.*\u003c\/p\u003e\u003cp\u003eEffective methylation must occur to maintain a normal level of homocysteine.* A deficiency in the cofactors that metabolize homocysteine is commonly seen in the elderly, thus resulting in increased homocysteine levels in the aging population. An elevated homocysteine level associated with aging, as well as less than optimal levels of folic acid and vitamins B6 and B12, often result in the inefficient methylation of numerous substances, such as DNA and proteins, which in turn decreases the integrity of vascular structures and neurons.* Providing the nutritional cofactors for the efficient metabolism of homocysteine also provides support for a healthy brain.*\u003c\/p\u003e\u003cp\u003eA number of biochemical imbalances that raise the level of homocysteine can be addressed by supplementing with appropriate nutrient cofactors. For example, folic acid (as L-5-methyltetrahydrofolate), vitamin B12 (as methylcobalamin), and betaine (trimethylglycine) help recycle homocysteine to the amino acid methionine, while the recycling of homocysteine into the beneficial amino acids cysteine and taurine is facilitated by pyridoxal 5'-phosphate (the active form of vitamin B6).* Studies have shown these nutrients help maintain a normal level of homocysteine in the blood.*\u003c\/p\u003e\u003cp\u003eBecause homocysteine levels can be higher in individuals in which the enzymatic reaction that converts folic acid to the active methyl donor L-5-methyltetrahydrofolate (5-MTHF) does not function properly, Methyl-Guard contains 400 mcg of active 5-MTHF per capsule.*\u003c\/p\u003e\u003ch3\u003eSuggested Use:\u003c\/h3\u003e\u003cp\u003eTake 3 capsules two times daily or as recommended by your health-care practitioner.\u003c\/p\u003e\u003ch3\u003eWarnings:\u003c\/h3\u003e\u003cp\u003e\u003cstrong\u003eALLERGY WARNING\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eThis product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003ePREGNANCY\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003eIf pregnant, consult your health-care practitioner before using this product.\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eINTERACTIONS\u003c\/strong\u003e\u003c\/p\u003e\u003cp\u003e5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic activity; however, this folate source has not been shown to interfere with the anti-inflammatory activity of methotrexate. 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